The serological diagnosis of infectious diseases characterized by persistent fever is based on the agglutination reaction which undergoes between the antigen and specific antibodies which may be present in the patient’s serum.
The Widal reaction allows the diagnosis of infections caused by Salmonella typhi, Salmonella paratyphi Groups A, B and C.
The method has been further developed through the adoption of the somatic O and flagellar H antigens.
The Wright reaction allows the diagnosis of Brucellosis (Maltese or Mediterranean Fever) caused by 3 strains di Brucella (melitensis, abortus and suis).
The Weil-Felix reaction allows the diagnosis of Rickettsiosis and is based on the fact that three strains of Proteus (OX19, OX2 and OXK), which share somatic antigenic components with Rickettsia, are agglutinated by antibodies present in the serum of infected patients.
Listeria plus is a tube agglutination assay for titration of antibodies against Listeria.
rigorous controls on the antigenic characteristics of bacterial strains used guarantee high sensitivity and specificity of the reaction
the stable coloured bacterial suspensions allow unequivocal readings in both the rapid slide tests and the microplate titrations
concordance of results
results obtained with the rapid test and with the microplate titration method are in agreement with the reference test-tube method