Systems Validation, Lyophilization, Bacterial cultures, Setting up of Immunization Protocols.

Systems Validation

Systems Validation

Sclavo’s Laboratory for Systems Analytical Validation was established aiming to offer a wider and more complete service to its own actual and future partners (distributors, customers, end-users).

Our Lab is specialized in the validation and certification of applications developed for its own-manufactured reagents to any available models of analytical instrumentation.

Therefore, Sclavo is not only able to provide products with Certified Quality but also Certified Applications of our reagents for specific laboratory instrument.

Lyophilization

Lyophilization

or cryodesiccation, is a dehydration process typically used to preserve a perishable material or make the material more convenient for transport.

Freeze-drying works by freezing the material and then reducing the surrounding pressure to allow the frozen water in the material to sublimate directly from the solid phase to the gas phase.

The process is applicable to chemical reagents, bacterial strains, immune-sera, antigenic suspensions and other products.

Fermentation

Fermentation

Aerobic cultures fermentation in stainless steel modern fermenters with the monitoring both of supplements addition and of the reaction environment.

Possibility of:

  • bacterial cultures complete recovering
  • concentration of the growth medium
  • separation and concentration of the secreted proteins.
Immune sera production

Immune sera production

Development of highly standardized immunization protocols (using protein nature or based on inactivated bacterial suspensions vaccines) for obtaining immune sera.

Availability of already standardized protocols for Salmonella anti serum (typhi O and H, Paratyphi AO, AH, BO, BH, CO, CH etc. etc.), Brucella, Listeria, Legionella, Shigella (sonnei, boydii, dysenteriae, flexnerii), Escherichia coli, Streptococcus (groups A, B, C, D, F, G).

Possibility on demand to prepare immune sera for other antigens or bacterial species.